Well spotted, the 2001" logo is an upside down bull's head symbol representing Baal the lord of this world, who was sometimes worshipped by the ancients in the form of the bull.
In the film Baal is represented by HAL, who is directing the secret mission.
At one point in the film Dave Bowman sees his refelction in HAL's red eye. You don't need to look hard to see Baal's horns! LOL:
Thanks for bringing this to light Jer! Keep up your sharp observations!